locus-tag	class	description
AFMDGAFA_00002	COG0592	DNA-directed DNA polymerase activity
AFMDGAFA_00004	COG0187	DNA topoisomerase II activity
AFMDGAFA_00006	COG0586	Pfam SNARE associated Golgi protein
AFMDGAFA_00007	COG0488	(ABC) transporter
AFMDGAFA_00012	COG0596	Alpha beta hydrolase
AFMDGAFA_00013	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AFMDGAFA_00014	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFMDGAFA_00022	COG0733	neurotransmitter:sodium symporter activity
AFMDGAFA_00030	COG2233	PERMEase
AFMDGAFA_00033	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFMDGAFA_00040	COG2814	Major facilitator Superfamily
AFMDGAFA_00041	COG0656	L-ascorbic acid biosynthetic process
AFMDGAFA_00042	COG0583	DNA-binding transcription factor activity
AFMDGAFA_00044	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AFMDGAFA_00045	COG1064	alcohol dehydrogenase
AFMDGAFA_00046	COG2818	Glycosylase
AFMDGAFA_00049	COG1194	a g-specific adenine glycosylase
AFMDGAFA_00053	COG2983	Belongs to the UPF0260 family
AFMDGAFA_00054	COG2133	pyrroloquinoline quinone binding
AFMDGAFA_00055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AFMDGAFA_00056	COG2116	formate transmembrane transporter activity
AFMDGAFA_00060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFMDGAFA_00061	COG1335	isochorismatase
AFMDGAFA_00062	COG0385	Bile acid
AFMDGAFA_00063	COG0534	Mate efflux family protein
AFMDGAFA_00064	COG1683	Conserved Protein
AFMDGAFA_00068	COG0625	glutathione transferase activity
AFMDGAFA_00070	COG1113	amino acid transport
AFMDGAFA_00072	COG0523	cobalamin synthesis protein
AFMDGAFA_00074	COG2188	Transcriptional regulator
AFMDGAFA_00080	COG0010	Belongs to the arginase family
AFMDGAFA_00084	COG1280	lysine exporter protein (LysE YggA)
AFMDGAFA_00088	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AFMDGAFA_00090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AFMDGAFA_00091	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AFMDGAFA_00100	COG0753	catalase activity
AFMDGAFA_00110	COG0534	Mate efflux family protein
AFMDGAFA_00111	COG0436	Aminotransferase
AFMDGAFA_00112	COG2733	membrane
AFMDGAFA_00115	COG2918	glutathione biosynthetic process
AFMDGAFA_00118	COG1388	LysM domain
AFMDGAFA_00118	COG1705	Flagellar rod assembly protein muramidase FlgJ
AFMDGAFA_00125	COG3150	esterase
AFMDGAFA_00127	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AFMDGAFA_00129	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AFMDGAFA_00131	COG2233	PERMEase
AFMDGAFA_00132	COG2351	hydroxyisourate hydrolase activity
AFMDGAFA_00139	COG3706	GGDEF domain
AFMDGAFA_00142	COG1393	Belongs to the ArsC family
AFMDGAFA_00148	COG0189	ligase activity
AFMDGAFA_00152	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AFMDGAFA_00154	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFMDGAFA_00157	COG4942	peptidase
AFMDGAFA_00159	COG0508	dehydrogenase complex catalyzes the overall conversion of
AFMDGAFA_00162	COG2119	membrane
AFMDGAFA_00163	COG4774	siderophore transport
AFMDGAFA_00164	COG0426	domain, Protein
AFMDGAFA_00164	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFMDGAFA_00169	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AFMDGAFA_00174	COG1902	pentaerythritol trinitrate reductase activity
AFMDGAFA_00175	COG1519	Transferase
AFMDGAFA_00179	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AFMDGAFA_00180	COG1335	isochorismatase
AFMDGAFA_00181	COG1522	sequence-specific DNA binding
AFMDGAFA_00186	COG0784	Response regulator, receiver
AFMDGAFA_00186	COG2198	Histidine kinase
AFMDGAFA_00186	COG2205	protein histidine kinase activity
AFMDGAFA_00187	COG3162	membrane
AFMDGAFA_00188	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFMDGAFA_00190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AFMDGAFA_00193	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AFMDGAFA_00194	COG1309	transcriptional regulator
AFMDGAFA_00198	COG0351	phosphomethylpyrimidine kinase
AFMDGAFA_00198	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AFMDGAFA_00198	COG0352	thiamine-phosphate diphosphorylase activity
AFMDGAFA_00200	COG2814	Major facilitator Superfamily
AFMDGAFA_00203	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AFMDGAFA_00205	COG1113	amino acid transport
AFMDGAFA_00207	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFMDGAFA_00208	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_00210	COG1335	isochorismatase
AFMDGAFA_00217	COG2814	Major facilitator Superfamily
AFMDGAFA_00218	COG0583	DNA-binding transcription factor activity
AFMDGAFA_00222	COG0667	Aldo Keto reductase
AFMDGAFA_00223	COG0667	Aldo Keto reductase
AFMDGAFA_00229	COG1733	regulation of RNA biosynthetic process
AFMDGAFA_00235	COG1733	regulation of RNA biosynthetic process
AFMDGAFA_00236	COG2249	NAD(P)H dehydrogenase (quinone) activity
AFMDGAFA_00240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AFMDGAFA_00241	COG2207	Transcriptional regulator
AFMDGAFA_00252	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AFMDGAFA_00255	COG2329	Antibiotic biosynthesis monooxygenase
AFMDGAFA_00261	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AFMDGAFA_00267	COG0427	acetyl-CoA hydrolase
AFMDGAFA_00271	COG0659	secondary active sulfate transmembrane transporter activity
AFMDGAFA_00272	COG4221	oxidoreductase activity
AFMDGAFA_00277	COG0488	(ABC) transporter
AFMDGAFA_00290	COG0833	amino acid
AFMDGAFA_00299	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AFMDGAFA_00300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AFMDGAFA_00303	COG2226	methyltransferase
AFMDGAFA_00313	COG0067	glutamate synthase
AFMDGAFA_00313	COG0069	glutamate synthase activity
AFMDGAFA_00313	COG0070	glutamate synthase
AFMDGAFA_00314	COG0493	'glutamate synthase
AFMDGAFA_00316	COG1704	LemA family
AFMDGAFA_00317	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AFMDGAFA_00319	COG4969	Belongs to the N-Me-Phe pilin family
AFMDGAFA_00320	COG3307	-O-antigen
AFMDGAFA_00324	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AFMDGAFA_00326	COG0194	GDP metabolic process
AFMDGAFA_00336	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AFMDGAFA_00340	COG5380	lipid catabolic process
AFMDGAFA_00341	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AFMDGAFA_00346	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AFMDGAFA_00347	COG0277	FAD linked oxidase domain protein
AFMDGAFA_00349	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AFMDGAFA_00350	COG2249	NAD(P)H dehydrogenase (quinone) activity
AFMDGAFA_00353	COG1289	transmembrane transporter activity
AFMDGAFA_00355	COG0628	permease
AFMDGAFA_00362	COG0833	amino acid
AFMDGAFA_00363	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AFMDGAFA_00364	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AFMDGAFA_00366	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_00374	COG0583	DNA-binding transcription factor activity
AFMDGAFA_00383	COG0517	IMP dehydrogenase activity
AFMDGAFA_00384	COG1983	PspC domain protein
AFMDGAFA_00386	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_00389	COG0408	coproporphyrinogen oxidase activity
AFMDGAFA_00393	COG0513	Belongs to the DEAD box helicase family
AFMDGAFA_00395	COG1127	ABC transporter
AFMDGAFA_00396	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AFMDGAFA_00398	COG2854	intermembrane phospholipid transfer
AFMDGAFA_00400	COG0598	Magnesium transport protein CorA
AFMDGAFA_00402	COG0494	nUDIX hydrolase
AFMDGAFA_00403	COG1040	competence protein
AFMDGAFA_00404	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AFMDGAFA_00408	COG1946	Acyl-CoA thioesterase
AFMDGAFA_00409	COG1301	dicarboxylic acid transport
AFMDGAFA_00412	COG1959	2 iron, 2 sulfur cluster binding
AFMDGAFA_00413	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFMDGAFA_00413	COG1017	nitric oxide dioxygenase activity
AFMDGAFA_00414	COG0433	COG0433 Predicted ATPase
AFMDGAFA_00415	COG0626	cystathionine gamma-synthase activity
AFMDGAFA_00446	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_00447	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AFMDGAFA_00454	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AFMDGAFA_00455	COG0339	signal peptide processing
AFMDGAFA_00456	COG0557	exoribonuclease II activity
AFMDGAFA_00466	COG2169	Transcriptional regulator
AFMDGAFA_00467	COG0697	spore germination
AFMDGAFA_00468	COG1295	ribonuclease BN
AFMDGAFA_00475	COG1702	phosphate starvation-inducible protein PhoH
AFMDGAFA_00477	COG0741	lytic transglycosylase activity
AFMDGAFA_00477	COG1196	nuclear chromosome segregation
AFMDGAFA_00477	COG0739	heme binding
AFMDGAFA_00483	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AFMDGAFA_00484	COG1183	phosphatidylcholine synthase activity
AFMDGAFA_00493	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_00494	COG1309	transcriptional regulator
AFMDGAFA_00497	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AFMDGAFA_00498	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_00502	COG2969	positive regulation of protein catabolic process
AFMDGAFA_00504	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AFMDGAFA_00506	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AFMDGAFA_00507	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AFMDGAFA_00508	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AFMDGAFA_00512	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AFMDGAFA_00514	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFMDGAFA_00515	COG1408	metallophosphoesterase
AFMDGAFA_00517	COG2199	diguanylate cyclase activity
AFMDGAFA_00529	COG1607	acyl-coa hydrolase
AFMDGAFA_00536	COG3013	Belongs to the UPF0304 family
AFMDGAFA_00553	COG2205	protein histidine kinase activity
AFMDGAFA_00556	COG2132	Multicopper oxidase
AFMDGAFA_00561	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AFMDGAFA_00570	COG0582	viral genome integration into host DNA
AFMDGAFA_00575	COG2350	Protein conserved in bacteria
AFMDGAFA_00577	COG0613	PHP domain protein
AFMDGAFA_00578	COG3781	membrane
AFMDGAFA_00580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AFMDGAFA_00581	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AFMDGAFA_00583	COG1862	Preprotein translocase
AFMDGAFA_00597	COG2205	protein histidine kinase activity
AFMDGAFA_00598	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AFMDGAFA_00602	COG0726	polysaccharide deacetylase
AFMDGAFA_00603	COG0463	Glycosyl transferase, family 2
AFMDGAFA_00604	COG0438	transferase activity, transferring glycosyl groups
AFMDGAFA_00607	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AFMDGAFA_00617	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_00618	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_00620	COG2205	protein histidine kinase activity
AFMDGAFA_00621	COG0745	RESPONSE REGULATOR receiver
AFMDGAFA_00622	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AFMDGAFA_00626	COG2096	Adenosyltransferase
AFMDGAFA_00627	COG4206	TonB-dependent receptor
AFMDGAFA_00637	COG0285	dihydrofolate synthase activity
AFMDGAFA_00641	COG0450	alkyl hydroperoxide reductase
AFMDGAFA_00644	COG0477	Major facilitator Superfamily
AFMDGAFA_00645	COG1272	protein, Hemolysin III
AFMDGAFA_00647	COG2153	protein acetylation
AFMDGAFA_00651	COG0183	Belongs to the thiolase family
AFMDGAFA_00652	COG2207	Transcriptional regulator
AFMDGAFA_00653	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AFMDGAFA_00656	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AFMDGAFA_00660	COG0183	Belongs to the thiolase family
AFMDGAFA_00664	COG1690	Belongs to the RtcB family
AFMDGAFA_00666	COG0833	amino acid
AFMDGAFA_00668	COG2233	PERMEase
AFMDGAFA_00669	COG1217	gtp-binding protein TYPA
AFMDGAFA_00674	COG2094	Belongs to the DNA glycosylase MPG family
AFMDGAFA_00675	COG4772	TonB-dependent receptor
AFMDGAFA_00676	COG1902	pentaerythritol trinitrate reductase activity
AFMDGAFA_00679	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AFMDGAFA_00680	COG0354	folic acid binding
AFMDGAFA_00682	COG3189	MarR family transcriptional regulator
AFMDGAFA_00683	COG2824	Alkylphosphonate utilization operon protein PhnA
AFMDGAFA_00684	COG3422	double-strand break repair
AFMDGAFA_00692	COG0840	transmembrane signaling receptor activity
AFMDGAFA_00696	COG5510	response to toxic substance
AFMDGAFA_00698	COG2832	Protein of unknown function (DUF454)
AFMDGAFA_00699	COG1376	ErfK ybiS ycfS ynhG family protein
AFMDGAFA_00707	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AFMDGAFA_00709	COG1289	transmembrane transporter activity
AFMDGAFA_00710	COG2814	Major facilitator Superfamily
AFMDGAFA_00713	COG1115	amino acid carrier protein
AFMDGAFA_00714	COG1752	Esterase of the alpha-beta hydrolase superfamily
AFMDGAFA_00715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AFMDGAFA_00716	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AFMDGAFA_00717	COG3590	peptidase
AFMDGAFA_00722	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFMDGAFA_00724	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFMDGAFA_00725	COG1077	Cell shape determining protein MreB Mrl
AFMDGAFA_00726	COG1792	Involved in formation and maintenance of cell shape
AFMDGAFA_00727	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AFMDGAFA_00728	COG0424	maF-like protein
AFMDGAFA_00729	COG1530	ribonuclease E activity
AFMDGAFA_00731	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AFMDGAFA_00733	COG0560	Phosphoserine phosphatase
AFMDGAFA_00735	COG2249	NAD(P)H dehydrogenase (quinone) activity
AFMDGAFA_00740	COG2207	Transcriptional regulator
AFMDGAFA_00744	COG1113	amino acid transport
AFMDGAFA_00745	COG2828	Protein conserved in bacteria
AFMDGAFA_00746	COG0142	geranyltranstransferase activity
AFMDGAFA_00747	COG2315	Protein conserved in bacteria
AFMDGAFA_00750	COG1752	Esterase of the alpha-beta hydrolase superfamily
AFMDGAFA_00754	COG2194	sulfuric ester hydrolase activity
AFMDGAFA_00755	COG0745	RESPONSE REGULATOR receiver
AFMDGAFA_00756	COG0642	Histidine kinase
AFMDGAFA_00759	COG0583	DNA-binding transcription factor activity
AFMDGAFA_00763	COG0525	valine-tRNA ligase activity
AFMDGAFA_00765	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_00767	COG0393	Putative heavy-metal-binding
AFMDGAFA_00768	COG0393	Putative heavy-metal-binding
AFMDGAFA_00769	COG1538	Outer membrane efflux protein
AFMDGAFA_00771	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFMDGAFA_00772	COG0671	phosphoesterase, PA-phosphatase related
AFMDGAFA_00777	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AFMDGAFA_00780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AFMDGAFA_00780	COG1648	precorrin-2 dehydrogenase activity
AFMDGAFA_00781	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AFMDGAFA_00782	COG1733	regulation of RNA biosynthetic process
AFMDGAFA_00784	COG0531	amino acid
AFMDGAFA_00787	COG0321	lipoyl(octanoyl) transferase activity
AFMDGAFA_00788	COG2921	Belongs to the UPF0250 family
AFMDGAFA_00796	COG2009	succinate dehydrogenase
AFMDGAFA_00797	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AFMDGAFA_00798	COG1053	succinate dehydrogenase
AFMDGAFA_00799	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AFMDGAFA_00802	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AFMDGAFA_00807	COG2354	Protein conserved in bacteria
AFMDGAFA_00808	COG2321	neutral zinc metallopeptidase
AFMDGAFA_00812	COG2843	Capsule synthesis protein
AFMDGAFA_00817	COG0251	oxidation-reduction process
AFMDGAFA_00818	COG1309	transcriptional regulator
AFMDGAFA_00821	COG0505	Belongs to the CarA family
AFMDGAFA_00826	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFMDGAFA_00827	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AFMDGAFA_00837	COG0477	Major facilitator Superfamily
AFMDGAFA_00838	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFMDGAFA_00841	COG1597	lipid kinase activity
AFMDGAFA_00846	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFMDGAFA_00847	COG0584	glycerophosphoryl diester phosphodiesterase
AFMDGAFA_00851	COG0741	lytic transglycosylase activity
AFMDGAFA_00855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AFMDGAFA_00858	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AFMDGAFA_00860	COG3811	Belongs to the UPF0386 family
AFMDGAFA_00872	COG0778	Nitroreductase
AFMDGAFA_00875	COG1929	Belongs to the glycerate kinase type-1 family
AFMDGAFA_00876	COG0243	molybdopterin cofactor binding
AFMDGAFA_00877	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AFMDGAFA_00878	COG3339	Conserved Protein
AFMDGAFA_00880	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AFMDGAFA_00883	COG1113	amino acid transport
AFMDGAFA_00885	COG0019	diaminopimelate decarboxylase activity
AFMDGAFA_00887	COG1280	lysine exporter protein (LysE YggA)
AFMDGAFA_00888	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AFMDGAFA_00894	COG0463	Glycosyl transferase, family 2
AFMDGAFA_00898	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFMDGAFA_00905	COG4591	ABC-type transport system involved in lipoprotein release permease component
AFMDGAFA_00906	COG1136	(ABC) transporter
AFMDGAFA_00907	COG0658	competence protein
AFMDGAFA_00907	COG2333	competence protein COMEC
AFMDGAFA_00909	COG0616	signal peptide processing
AFMDGAFA_00909	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AFMDGAFA_00910	COG0596	Alpha beta hydrolase
AFMDGAFA_00911	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AFMDGAFA_00913	COG0628	permease
AFMDGAFA_00920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFMDGAFA_00924	COG0823	Involved in the tonB-independent uptake of proteins
AFMDGAFA_00928	COG0824	Thioesterase
AFMDGAFA_00929	COG1473	amidohydrolase
AFMDGAFA_00933	COG0047	phosphoribosylformylglycinamidine synthase activity
AFMDGAFA_00933	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFMDGAFA_00934	COG2814	Major facilitator Superfamily
AFMDGAFA_00938	COG1169	isochorismate synthase
AFMDGAFA_00939	COG1535	isochorismatase
AFMDGAFA_00939	COG3433	isochorismatase activity
AFMDGAFA_00940	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_00941	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AFMDGAFA_00942	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AFMDGAFA_00943	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AFMDGAFA_00944	COG1021	2,3-dihydroxybenzoate-AMP ligase
AFMDGAFA_00945	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AFMDGAFA_00946	COG0019	diaminopimelate decarboxylase activity
AFMDGAFA_00951	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AFMDGAFA_00952	COG4774	siderophore transport
AFMDGAFA_00955	COG0534	Mate efflux family protein
AFMDGAFA_00957	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFMDGAFA_00972	COG1024	Enoyl-CoA hydratase
AFMDGAFA_00973	COG1056	cytidyltransferase-related domain
AFMDGAFA_00973	COG1051	belongs to the nudix hydrolase family
AFMDGAFA_00975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AFMDGAFA_00978	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AFMDGAFA_00981	COG4625	pathogenesis
AFMDGAFA_00982	COG0583	DNA-binding transcription factor activity
AFMDGAFA_00983	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AFMDGAFA_00984	COG4208	sulfate ABC transporter
AFMDGAFA_00985	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AFMDGAFA_00987	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AFMDGAFA_00988	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AFMDGAFA_00989	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AFMDGAFA_00993	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFMDGAFA_00995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AFMDGAFA_00997	COG0681	Belongs to the peptidase S26 family
AFMDGAFA_01000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AFMDGAFA_01002	COG1381	Involved in DNA repair and RecF pathway recombination
AFMDGAFA_01003	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AFMDGAFA_01004	COG4445	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)
AFMDGAFA_01005	COG4221	oxidoreductase activity
AFMDGAFA_01010	COG0443	Heat shock 70 kDa protein
AFMDGAFA_01012	COG0436	Aminotransferase
AFMDGAFA_01016	COG0556	nucleotide-excision repair
AFMDGAFA_01027	COG2070	2-Nitropropane dioxygenase
AFMDGAFA_01033	COG1215	transferase activity, transferring glycosyl groups
AFMDGAFA_01036	COG0415	Belongs to the DNA photolyase family
AFMDGAFA_01038	COG1252	NADH dehydrogenase
AFMDGAFA_01039	COG1686	Belongs to the peptidase S11 family
AFMDGAFA_01042	COG1187	pseudouridine synthase activity
AFMDGAFA_01047	COG0477	Major facilitator Superfamily
AFMDGAFA_01048	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01049	COG1823	symporter activity
AFMDGAFA_01051	COG0612	Peptidase, M16
AFMDGAFA_01056	COG0352	thiamine-phosphate diphosphorylase activity
AFMDGAFA_01063	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFMDGAFA_01065	COG2249	NAD(P)H dehydrogenase (quinone) activity
AFMDGAFA_01068	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFMDGAFA_01069	COG0076	glutamate decarboxylase activity
AFMDGAFA_01071	COG1522	sequence-specific DNA binding
AFMDGAFA_01072	COG3961	Belongs to the TPP enzyme family
AFMDGAFA_01073	COG1113	amino acid transport
AFMDGAFA_01074	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AFMDGAFA_01075	COG0573	inorganic phosphate transmembrane transporter activity
AFMDGAFA_01077	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AFMDGAFA_01078	COG0616	signal peptide processing
AFMDGAFA_01085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AFMDGAFA_01086	COG1686	Belongs to the peptidase S11 family
AFMDGAFA_01091	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01092	COG1067	ATP-dependent peptidase activity
AFMDGAFA_01097	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AFMDGAFA_01101	COG1966	Carbon starvation protein
AFMDGAFA_01102	COG2879	small protein
AFMDGAFA_01111	COG1335	isochorismatase
AFMDGAFA_01112	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01115	COG0596	Alpha beta hydrolase
AFMDGAFA_01117	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AFMDGAFA_01124	COG1741	Belongs to the pirin family
AFMDGAFA_01126	COG2964	Protein conserved in bacteria
AFMDGAFA_01128	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AFMDGAFA_01129	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AFMDGAFA_01132	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFMDGAFA_01133	COG4605	iron ion homeostasis
AFMDGAFA_01134	COG4604	ABC transporter, ATP-binding protein
AFMDGAFA_01135	COG4607	ABC-type enterochelin transport system periplasmic component
AFMDGAFA_01136	COG4774	siderophore transport
AFMDGAFA_01138	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AFMDGAFA_01139	COG1021	2,3-dihydroxybenzoate-AMP ligase
AFMDGAFA_01140	COG3433	isochorismatase activity
AFMDGAFA_01140	COG1535	isochorismatase
AFMDGAFA_01143	COG1132	(ABC) transporter
AFMDGAFA_01144	COG1132	(ABC) transporter
AFMDGAFA_01145	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AFMDGAFA_01150	COG3739	integral membrane protein
AFMDGAFA_01155	COG0302	gtp cyclohydrolase
AFMDGAFA_01157	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AFMDGAFA_01164	COG0512	Glutamine amidotransferase of anthranilate synthase
AFMDGAFA_01167	COG0174	glutamine synthetase
AFMDGAFA_01169	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AFMDGAFA_01176	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AFMDGAFA_01177	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AFMDGAFA_01178	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFMDGAFA_01182	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AFMDGAFA_01183	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AFMDGAFA_01184	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AFMDGAFA_01187	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_01188	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AFMDGAFA_01189	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AFMDGAFA_01192	COG2223	nitrite transmembrane transporter activity
AFMDGAFA_01194	COG0024	Methionine aminopeptidase
AFMDGAFA_01196	COG0052	Belongs to the universal ribosomal protein uS2 family
AFMDGAFA_01199	COG2207	Transcriptional regulator
AFMDGAFA_01205	COG2951	lytic endotransglycosylase activity
AFMDGAFA_01206	COG0772	Belongs to the SEDS family
AFMDGAFA_01209	COG0842	Transport permease protein
AFMDGAFA_01210	COG1131	(ABC) transporter
AFMDGAFA_01218	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFMDGAFA_01221	COG4215	(ABC) transporter
AFMDGAFA_01222	COG4160	amino acid transport
AFMDGAFA_01223	COG4598	ABC transporter
AFMDGAFA_01225	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AFMDGAFA_01226	COG0826	peptidase U32
AFMDGAFA_01227	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AFMDGAFA_01230	COG1720	tRNA m6t6A37 methyltransferase activity
AFMDGAFA_01232	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AFMDGAFA_01235	COG0642	Histidine kinase
AFMDGAFA_01237	COG0494	nUDIX hydrolase
AFMDGAFA_01239	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AFMDGAFA_01240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFMDGAFA_01241	COG3139	Protein of unknown function (DUF1315)
AFMDGAFA_01242	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AFMDGAFA_01243	COG1301	dicarboxylic acid transport
AFMDGAFA_01244	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_01245	COG2819	hydrolase of the alpha beta superfamily
AFMDGAFA_01247	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AFMDGAFA_01249	COG2195	Cleaves the N-terminal amino acid of tripeptides
AFMDGAFA_01253	COG1690	Belongs to the RtcB family
AFMDGAFA_01254	COG1234	tRNA 3'-trailer cleavage
AFMDGAFA_01255	COG4650	regulator
AFMDGAFA_01261	COG2363	Small membrane protein
AFMDGAFA_01265	COG0513	Belongs to the DEAD box helicase family
AFMDGAFA_01267	COG0778	Nitroreductase
AFMDGAFA_01273	COG1286	toxin biosynthetic process
AFMDGAFA_01278	COG4783	chaperone-mediated protein folding
AFMDGAFA_01279	COG1610	YqeY-like protein
AFMDGAFA_01286	COG0515	serine threonine protein kinase
AFMDGAFA_01286	COG2815	serine threonine protein kinase
AFMDGAFA_01300	COG3111	PFAM Bacterial OB fold (BOF) protein
AFMDGAFA_01306	COG0786	glutamate:sodium symporter activity
AFMDGAFA_01308	COG2186	Transcriptional regulator
AFMDGAFA_01318	COG0477	Major facilitator Superfamily
AFMDGAFA_01319	COG1051	belongs to the nudix hydrolase family
AFMDGAFA_01326	COG2995	paraquat-inducible protein a
AFMDGAFA_01327	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AFMDGAFA_01327	COG3008	intermembrane lipid transfer
AFMDGAFA_01330	COG1794	racemase activity, acting on amino acids and derivatives
AFMDGAFA_01336	COG1301	dicarboxylic acid transport
AFMDGAFA_01338	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFMDGAFA_01339	COG2011	ABC-type metal ion transport system permease component
AFMDGAFA_01340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFMDGAFA_01341	COG1464	Belongs to the NlpA lipoprotein family
AFMDGAFA_01342	COG0151	Belongs to the GarS family
AFMDGAFA_01343	COG0138	bifunctional purine biosynthesis protein purh
AFMDGAFA_01344	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AFMDGAFA_01350	COG2308	Evidence 4 Homologs of previously reported genes of
AFMDGAFA_01352	COG1305	Transglutaminase-like
AFMDGAFA_01354	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFMDGAFA_01355	COG0305	Participates in initiation and elongation during chromosome replication
AFMDGAFA_01360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AFMDGAFA_01362	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AFMDGAFA_01363	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AFMDGAFA_01369	COG0726	polysaccharide deacetylase
AFMDGAFA_01369	COG1649	PFAM Uncharacterised BCR, COG1649
AFMDGAFA_01370	COG1215	transferase activity, transferring glycosyl groups
AFMDGAFA_01371	COG3658	cytochrome
AFMDGAFA_01373	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFMDGAFA_01376	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01382	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_01383	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AFMDGAFA_01384	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFMDGAFA_01387	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AFMDGAFA_01390	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AFMDGAFA_01391	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AFMDGAFA_01392	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AFMDGAFA_01393	COG2205	protein histidine kinase activity
AFMDGAFA_01394	COG0745	RESPONSE REGULATOR receiver
AFMDGAFA_01395	COG0174	glutamine synthetase
AFMDGAFA_01399	COG0729	surface antigen
AFMDGAFA_01404	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AFMDGAFA_01405	COG2814	Major facilitator Superfamily
AFMDGAFA_01408	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01411	COG1187	pseudouridine synthase activity
AFMDGAFA_01415	COG0802	atpase or kinase
AFMDGAFA_01416	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AFMDGAFA_01418	COG1923	regulation of RNA biosynthetic process
AFMDGAFA_01419	COG0697	spore germination
AFMDGAFA_01424	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFMDGAFA_01425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AFMDGAFA_01425	COG0519	Catalyzes the synthesis of GMP from XMP
AFMDGAFA_01426	COG4302	ethanolamine ammonia-lyase activity
AFMDGAFA_01427	COG4303	Ethanolamine ammonia lyase large subunit
AFMDGAFA_01428	COG0531	amino acid
AFMDGAFA_01432	COG1454	alcohol dehydrogenase
AFMDGAFA_01433	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AFMDGAFA_01438	COG0308	aminopeptidase N
AFMDGAFA_01446	COG1605	Chorismate mutase
AFMDGAFA_01450	COG1309	transcriptional regulator
AFMDGAFA_01452	COG0668	transmembrane transport
AFMDGAFA_01458	COG4773	Receptor
AFMDGAFA_01462	COG0488	(ABC) transporter
AFMDGAFA_01468	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AFMDGAFA_01470	COG3135	benzoate transporter
AFMDGAFA_01471	COG1522	sequence-specific DNA binding
AFMDGAFA_01473	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AFMDGAFA_01476	COG0183	Belongs to the thiolase family
AFMDGAFA_01477	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_01478	COG2030	dehydratase
AFMDGAFA_01479	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AFMDGAFA_01482	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFMDGAFA_01485	COG0824	Thioesterase
AFMDGAFA_01486	COG1454	alcohol dehydrogenase
AFMDGAFA_01488	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFMDGAFA_01492	COG0069	glutamate synthase activity
AFMDGAFA_01523	COG3617	BRO family, N-terminal domain
AFMDGAFA_01530	COG5410	chromosome segregation
AFMDGAFA_01564	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFMDGAFA_01567	COG2814	Major facilitator Superfamily
AFMDGAFA_01570	COG0511	ligase activity, forming carbon-carbon bonds
AFMDGAFA_01573	COG1116	anion transmembrane transporter activity
AFMDGAFA_01573	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AFMDGAFA_01574	COG0745	RESPONSE REGULATOR receiver
AFMDGAFA_01576	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AFMDGAFA_01576	COG2146	nitrite reductase [NAD(P)H] activity
AFMDGAFA_01577	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AFMDGAFA_01578	COG0243	molybdopterin cofactor binding
AFMDGAFA_01581	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AFMDGAFA_01584	COG0521	Mo-molybdopterin cofactor biosynthetic process
AFMDGAFA_01584	COG0315	cyclic pyranopterin monophosphate synthase activity
AFMDGAFA_01585	COG0303	'Molybdopterin
AFMDGAFA_01587	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AFMDGAFA_01588	COG0697	spore germination
AFMDGAFA_01592	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AFMDGAFA_01593	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AFMDGAFA_01605	COG2204	response regulator
AFMDGAFA_01606	COG3852	Histidine kinase
AFMDGAFA_01610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFMDGAFA_01611	COG0575	Belongs to the CDS family
AFMDGAFA_01614	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AFMDGAFA_01618	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AFMDGAFA_01621	COG2137	regulation of response to DNA damage stimulus
AFMDGAFA_01623	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AFMDGAFA_01624	COG1011	Hydrolase
AFMDGAFA_01629	COG1522	sequence-specific DNA binding
AFMDGAFA_01631	COG1113	amino acid transport
AFMDGAFA_01634	COG0659	secondary active sulfate transmembrane transporter activity
AFMDGAFA_01635	COG2135	peptidase activity
AFMDGAFA_01638	COG5001	Diguanylate cyclase
AFMDGAFA_01638	COG3300	MHYT domain
AFMDGAFA_01641	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AFMDGAFA_01641	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AFMDGAFA_01642	COG1105	Belongs to the carbohydrate kinase PfkB family
AFMDGAFA_01643	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AFMDGAFA_01643	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AFMDGAFA_01649	COG0024	Methionine aminopeptidase
AFMDGAFA_01650	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01652	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AFMDGAFA_01653	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AFMDGAFA_01659	COG0552	protein localization to endoplasmic reticulum
AFMDGAFA_01661	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AFMDGAFA_01664	COG4890	Cyd operon protein YbgT
AFMDGAFA_01665	COG1294	oxidase, subunit
AFMDGAFA_01668	COG1585	Membrane protein implicated in regulation of membrane protease activity
AFMDGAFA_01670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AFMDGAFA_01671	COG4774	siderophore transport
AFMDGAFA_01674	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AFMDGAFA_01675	COG0569	domain protein
AFMDGAFA_01676	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AFMDGAFA_01682	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AFMDGAFA_01683	COG0542	response to heat
AFMDGAFA_01688	COG1902	pentaerythritol trinitrate reductase activity
AFMDGAFA_01688	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFMDGAFA_01697	COG2323	membrane
AFMDGAFA_01698	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AFMDGAFA_01700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AFMDGAFA_01701	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AFMDGAFA_01702	COG0183	Belongs to the thiolase family
AFMDGAFA_01703	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AFMDGAFA_01704	COG0596	Alpha beta hydrolase
AFMDGAFA_01705	COG2271	Major facilitator Superfamily
AFMDGAFA_01706	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AFMDGAFA_01707	COG3485	protocatechuate 3,4-dioxygenase
AFMDGAFA_01708	COG3485	protocatechuate 3,4-dioxygenase
AFMDGAFA_01709	COG0710	3-dehydroquinate dehydratase activity
AFMDGAFA_01710	COG3420	alginic acid biosynthetic process
AFMDGAFA_01711	COG3659	wide pore channel activity
AFMDGAFA_01712	COG4993	Dehydrogenase
AFMDGAFA_01714	COG2391	methyltransferase activity
AFMDGAFA_01717	COG1414	Transcriptional regulator
AFMDGAFA_01718	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01719	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_01724	COG2814	Major facilitator Superfamily
AFMDGAFA_01730	COG4638	Rieske (2fe-2S)
AFMDGAFA_01732	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_01734	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFMDGAFA_01736	COG3733	amine oxidase
AFMDGAFA_01738	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_01740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AFMDGAFA_01741	COG0183	Belongs to the thiolase family
AFMDGAFA_01742	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AFMDGAFA_01743	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AFMDGAFA_01745	COG4829	muconolactone delta-isomerase
AFMDGAFA_01746	COG4948	Mandelate Racemase Muconate Lactonizing
AFMDGAFA_01747	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01749	COG2186	Transcriptional regulator
AFMDGAFA_01753	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_01756	COG1902	pentaerythritol trinitrate reductase activity
AFMDGAFA_01756	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFMDGAFA_01758	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AFMDGAFA_01760	COG0789	Transcriptional regulator
AFMDGAFA_01765	COG1309	transcriptional regulator
AFMDGAFA_01766	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01767	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_01768	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_01769	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_01771	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_01773	COG0318	PFAM AMP-dependent synthetase and ligase
AFMDGAFA_01790	COG2188	Transcriptional regulator
AFMDGAFA_01793	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01796	COG1566	PFAM secretion protein HlyD family protein
AFMDGAFA_01799	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_01800	COG0129	dihydroxy-acid dehydratase activity
AFMDGAFA_01802	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01803	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AFMDGAFA_01805	COG2084	Dehydrogenase
AFMDGAFA_01806	COG2207	Transcriptional regulator
AFMDGAFA_01807	COG1064	alcohol dehydrogenase
AFMDGAFA_01809	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFMDGAFA_01810	COG1120	ATPase activity
AFMDGAFA_01831	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AFMDGAFA_01839	COG2856	Zn peptidase
AFMDGAFA_01849	COG2207	Transcriptional regulator
AFMDGAFA_01852	COG2205	protein histidine kinase activity
AFMDGAFA_01853	COG0745	RESPONSE REGULATOR receiver
AFMDGAFA_01854	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFMDGAFA_01855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AFMDGAFA_01872	COG3539	Fimbrial protein
AFMDGAFA_01878	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AFMDGAFA_01880	COG0753	catalase activity
AFMDGAFA_01883	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFMDGAFA_01895	COG1535	isochorismatase
AFMDGAFA_01895	COG3433	isochorismatase activity
AFMDGAFA_01896	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_01897	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AFMDGAFA_01898	COG4149	molybdate abc transporter
AFMDGAFA_01899	COG0725	ABC transporter, periplasmic molybdate-binding protein
AFMDGAFA_01901	COG4638	Rieske (2fe-2S)
AFMDGAFA_01902	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AFMDGAFA_01903	COG0543	2 iron, 2 sulfur cluster binding
AFMDGAFA_01903	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFMDGAFA_01906	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFMDGAFA_01908	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_01911	COG2207	Transcriptional regulator
AFMDGAFA_01912	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_01913	COG2610	gluconate transmembrane transporter activity
AFMDGAFA_01915	COG1309	transcriptional regulator
AFMDGAFA_01920	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01923	COG2031	fatty acid transporter
AFMDGAFA_01924	COG0183	Belongs to the thiolase family
AFMDGAFA_01925	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01926	COG0583	DNA-binding transcription factor activity
AFMDGAFA_01929	COG1027	Aspartate ammonia-lyase
AFMDGAFA_01931	COG0477	Major facilitator Superfamily
AFMDGAFA_01936	COG4521	taurine ABC transporter
AFMDGAFA_01939	COG2188	Transcriptional regulator
AFMDGAFA_01941	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AFMDGAFA_01942	COG1733	regulation of RNA biosynthetic process
AFMDGAFA_01943	COG2207	Transcriptional regulator
AFMDGAFA_01943	COG3708	Transcriptional regulator
AFMDGAFA_01946	COG0730	response to heat
AFMDGAFA_01948	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFMDGAFA_01948	COG3453	Protein conserved in bacteria
AFMDGAFA_01950	COG3781	membrane
AFMDGAFA_01951	COG1063	alcohol dehydrogenase
AFMDGAFA_01953	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AFMDGAFA_01954	COG0508	dehydrogenase complex catalyzes the overall conversion of
AFMDGAFA_01955	COG0022	dehydrogenase e1 component
AFMDGAFA_01956	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AFMDGAFA_01957	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AFMDGAFA_01960	COG3706	GGDEF domain
AFMDGAFA_01963	COG0133	tryptophan synthase activity
AFMDGAFA_01965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFMDGAFA_01971	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AFMDGAFA_01972	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AFMDGAFA_01977	COG2226	methyltransferase
AFMDGAFA_01988	COG0842	Transport permease protein
AFMDGAFA_01989	COG0842	Transport permease protein
AFMDGAFA_01990	COG1131	(ABC) transporter
AFMDGAFA_01993	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AFMDGAFA_01994	COG4773	Receptor
AFMDGAFA_01998	COG0730	response to heat
AFMDGAFA_01999	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AFMDGAFA_02002	COG0406	alpha-ribazole phosphatase activity
AFMDGAFA_02003	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AFMDGAFA_02006	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AFMDGAFA_02014	COG4264	IucA IucC family
AFMDGAFA_02015	COG4264	IucA IucC family
AFMDGAFA_02016	COG2814	Major facilitator Superfamily
AFMDGAFA_02019	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AFMDGAFA_02022	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_02023	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_02024	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AFMDGAFA_02025	COG2207	Transcriptional regulator
AFMDGAFA_02028	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AFMDGAFA_02029	COG0776	regulation of translation
AFMDGAFA_02034	COG0822	iron-sulfur transferase activity
AFMDGAFA_02035	COG0316	Belongs to the HesB IscA family
AFMDGAFA_02041	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AFMDGAFA_02043	COG2837	iron assimilation
AFMDGAFA_02045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AFMDGAFA_02046	COG0702	epimerase
AFMDGAFA_02053	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFMDGAFA_02055	COG0339	signal peptide processing
AFMDGAFA_02065	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AFMDGAFA_02105	COG0305	Participates in initiation and elongation during chromosome replication
AFMDGAFA_02120	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AFMDGAFA_02126	COG0776	regulation of translation
AFMDGAFA_02139	COG0084	hydrolase, TatD family'
AFMDGAFA_02143	COG1663	tetraacyldisaccharide 4'-kinase activity
AFMDGAFA_02144	COG1132	(ABC) transporter
AFMDGAFA_02146	COG0811	peptide transport
AFMDGAFA_02147	COG1475	DNA binding
AFMDGAFA_02148	COG1192	Involved in chromosome partitioning
AFMDGAFA_02150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AFMDGAFA_02153	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AFMDGAFA_02154	COG0191	fructose-bisphosphate aldolase activity
AFMDGAFA_02158	COG0424	maF-like protein
AFMDGAFA_02159	COG2850	peptidyl-arginine hydroxylation
AFMDGAFA_02161	COG0640	Transcriptional regulator
AFMDGAFA_02163	COG3619	membrane
AFMDGAFA_02164	COG3122	Protein conserved in bacteria
AFMDGAFA_02165	COG1132	(ABC) transporter
AFMDGAFA_02169	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AFMDGAFA_02170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFMDGAFA_02172	COG0506	proline dehydrogenase activity
AFMDGAFA_02172	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AFMDGAFA_02172	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AFMDGAFA_02173	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AFMDGAFA_02176	COG3698	Phosphodiester glycosidase
AFMDGAFA_02178	COG2353	YceI-like domain
AFMDGAFA_02180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AFMDGAFA_02189	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AFMDGAFA_02189	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AFMDGAFA_02194	COG3539	Fimbrial protein
AFMDGAFA_02195	COG3121	Chaperone
AFMDGAFA_02200	COG0697	spore germination
AFMDGAFA_02202	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AFMDGAFA_02210	COG1309	transcriptional regulator
AFMDGAFA_02215	COG1126	abc transporter atp-binding protein
AFMDGAFA_02216	COG0765	amino acid transport
AFMDGAFA_02217	COG0765	amino acid transport
AFMDGAFA_02222	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFMDGAFA_02223	COG1464	Belongs to the NlpA lipoprotein family
AFMDGAFA_02225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFMDGAFA_02226	COG2011	ABC-type metal ion transport system permease component
AFMDGAFA_02227	COG0012	GTP binding
AFMDGAFA_02232	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AFMDGAFA_02240	COG0386	Belongs to the glutathione peroxidase family
AFMDGAFA_02242	COG0436	Aminotransferase
AFMDGAFA_02243	COG1301	dicarboxylic acid transport
AFMDGAFA_02250	COG3634	alkyl hydroperoxide reductase activity
AFMDGAFA_02253	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02254	COG0798	PFAM Bile acid sodium symporter
AFMDGAFA_02255	COG0640	Transcriptional regulator
AFMDGAFA_02258	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AFMDGAFA_02260	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02262	COG1953	Uracil, thiamine, allantoin
AFMDGAFA_02264	COG2175	clavaminate synthase activity
AFMDGAFA_02265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AFMDGAFA_02266	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AFMDGAFA_02267	COG4521	taurine ABC transporter
AFMDGAFA_02269	COG0477	Major facilitator Superfamily
AFMDGAFA_02273	COG1271	oxidase subunit
AFMDGAFA_02274	COG1294	oxidase, subunit
AFMDGAFA_02275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AFMDGAFA_02279	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AFMDGAFA_02283	COG3052	prosthetic group binding
AFMDGAFA_02284	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AFMDGAFA_02286	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02288	COG2814	Major facilitator Superfamily
AFMDGAFA_02291	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AFMDGAFA_02292	COG1346	cytolysis
AFMDGAFA_02294	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02295	COG0625	glutathione transferase activity
AFMDGAFA_02296	COG0625	glutathione transferase activity
AFMDGAFA_02297	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02300	COG1045	serine acetyltransferase
AFMDGAFA_02301	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AFMDGAFA_02302	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AFMDGAFA_02305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AFMDGAFA_02306	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AFMDGAFA_02308	COG0765	amino acid transport
AFMDGAFA_02309	COG0765	amino acid transport
AFMDGAFA_02312	COG2205	protein histidine kinase activity
AFMDGAFA_02312	COG0784	Response regulator, receiver
AFMDGAFA_02320	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_02332	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02336	COG0318	PFAM AMP-dependent synthetase and ligase
AFMDGAFA_02337	COG1309	transcriptional regulator
AFMDGAFA_02338	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_02339	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AFMDGAFA_02340	COG1024	Enoyl-CoA hydratase
AFMDGAFA_02341	COG4770	biotin carboxylase activity
AFMDGAFA_02343	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02347	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AFMDGAFA_02348	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AFMDGAFA_02351	COG3842	ATPase activity
AFMDGAFA_02352	COG1840	ABC-type Fe3 transport system, periplasmic component
AFMDGAFA_02355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AFMDGAFA_02356	COG1414	Transcriptional regulator
AFMDGAFA_02358	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02359	COG3038	cytochrome b561
AFMDGAFA_02360	COG0753	catalase activity
AFMDGAFA_02369	COG3327	negative regulation of DNA-templated transcription, initiation
AFMDGAFA_02370	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AFMDGAFA_02371	COG0183	Belongs to the thiolase family
AFMDGAFA_02372	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFMDGAFA_02373	COG1024	Enoyl-CoA hydratase
AFMDGAFA_02374	COG1024	Enoyl-CoA hydratase
AFMDGAFA_02375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFMDGAFA_02376	COG2151	metal-sulfur cluster biosynthetic enzyme
AFMDGAFA_02377	COG3396	Phenylacetate-CoA oxygenase
AFMDGAFA_02378	COG3460	Phenylacetate-CoA oxygenase
AFMDGAFA_02379	COG3396	Phenylacetate-CoA oxygenase
AFMDGAFA_02380	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_02380	COG2030	dehydratase
AFMDGAFA_02381	COG1760	l-serine dehydratase
AFMDGAFA_02382	COG0531	amino acid
AFMDGAFA_02383	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_02388	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AFMDGAFA_02392	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFMDGAFA_02396	COG0789	Transcriptional regulator
AFMDGAFA_02398	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AFMDGAFA_02401	COG2807	transmembrane transport
AFMDGAFA_02402	COG0590	tRNA wobble adenosine to inosine editing
AFMDGAFA_02423	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AFMDGAFA_02429	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AFMDGAFA_02434	COG1733	regulation of RNA biosynthetic process
AFMDGAFA_02435	COG2249	NAD(P)H dehydrogenase (quinone) activity
AFMDGAFA_02436	COG0439	Biotin carboxylase
AFMDGAFA_02440	COG1063	alcohol dehydrogenase
AFMDGAFA_02442	COG1309	transcriptional regulator
AFMDGAFA_02446	COG0038	chloride channel
AFMDGAFA_02447	COG4770	biotin carboxylase activity
AFMDGAFA_02451	COG1914	H( )-stimulated, divalent metal cation uptake system
AFMDGAFA_02452	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02458	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFMDGAFA_02462	COG2814	Major facilitator Superfamily
AFMDGAFA_02467	COG1560	Kdo2-lipid A biosynthetic process
AFMDGAFA_02470	COG1522	sequence-specific DNA binding
AFMDGAFA_02473	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AFMDGAFA_02475	COG4122	O-methyltransferase activity
AFMDGAFA_02481	COG1538	Outer membrane efflux protein
AFMDGAFA_02482	COG1137	ATPase activity
AFMDGAFA_02483	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AFMDGAFA_02485	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AFMDGAFA_02486	COG0517	IMP dehydrogenase activity
AFMDGAFA_02486	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AFMDGAFA_02494	COG2814	Major facilitator Superfamily
AFMDGAFA_02501	COG1278	Cold shock
AFMDGAFA_02502	COG1280	lysine exporter protein (LysE YggA)
AFMDGAFA_02509	COG1570	exodeoxyribonuclease VII activity
AFMDGAFA_02520	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02521	COG4638	Rieske (2fe-2S)
AFMDGAFA_02522	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AFMDGAFA_02523	COG0543	2 iron, 2 sulfur cluster binding
AFMDGAFA_02523	COG0633	Ferredoxin
AFMDGAFA_02524	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_02525	COG3135	benzoate transporter
AFMDGAFA_02526	COG2814	Major facilitator Superfamily
AFMDGAFA_02529	COG1643	Atp-dependent helicase
AFMDGAFA_02530	COG0450	alkyl hydroperoxide reductase
AFMDGAFA_02532	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AFMDGAFA_02534	COG3634	alkyl hydroperoxide reductase activity
AFMDGAFA_02538	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AFMDGAFA_02539	COG0625	glutathione transferase activity
AFMDGAFA_02541	COG2885	chlorophyll binding
AFMDGAFA_02548	COG0542	response to heat
AFMDGAFA_02551	COG1765	OsmC-like protein
AFMDGAFA_02553	COG0667	Aldo Keto reductase
AFMDGAFA_02556	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AFMDGAFA_02587	COG3566	protein conserved in bacteria
AFMDGAFA_02592	COG3567	Phage-associated protein, HI1409 family
AFMDGAFA_02593	COG5410	chromosome segregation
AFMDGAFA_02609	COG4197	protein conserved in bacteria, prophage-related
AFMDGAFA_02610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AFMDGAFA_02620	COG0527	aspartate kinase activity
AFMDGAFA_02622	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFMDGAFA_02624	COG3038	cytochrome b561
AFMDGAFA_02625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AFMDGAFA_02626	COG2252	PERMEase
AFMDGAFA_02628	COG2072	flavoprotein involved in K transport
AFMDGAFA_02631	COG1741	Belongs to the pirin family
AFMDGAFA_02632	COG1309	transcriptional regulator
AFMDGAFA_02635	COG2072	flavoprotein involved in K transport
AFMDGAFA_02636	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AFMDGAFA_02645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFMDGAFA_02648	COG2814	Major facilitator Superfamily
AFMDGAFA_02649	COG1024	Enoyl-CoA hydratase
AFMDGAFA_02650	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_02652	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_02657	COG2186	Transcriptional regulator
AFMDGAFA_02658	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_02660	COG4948	Mandelate Racemase Muconate Lactonizing
AFMDGAFA_02661	COG2271	Major facilitator Superfamily
AFMDGAFA_02662	COG2721	sulfolactate sulfo-lyase activity
AFMDGAFA_02663	COG0697	spore germination
AFMDGAFA_02669	COG1113	amino acid transport
AFMDGAFA_02673	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_02677	COG0531	amino acid
AFMDGAFA_02679	COG1113	amino acid transport
AFMDGAFA_02691	COG0251	oxidation-reduction process
AFMDGAFA_02699	COG1902	pentaerythritol trinitrate reductase activity
AFMDGAFA_02699	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFMDGAFA_02702	COG2203	Gaf domain
AFMDGAFA_02702	COG4251	negative regulation of phosphorylation
AFMDGAFA_02702	COG5001	Diguanylate cyclase
AFMDGAFA_02702	COG3706	GGDEF domain
AFMDGAFA_02704	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AFMDGAFA_02708	COG4172	Belongs to the ABC transporter superfamily
AFMDGAFA_02709	COG4239	(ABC) transporter, permease
AFMDGAFA_02710	COG4174	ABC transporter (Permease)
AFMDGAFA_02712	COG1388	LysM domain
AFMDGAFA_02712	COG1388	LysM domain
AFMDGAFA_02712	COG0741	lytic transglycosylase activity
AFMDGAFA_02712	COG0741	lytic transglycosylase activity
AFMDGAFA_02713	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AFMDGAFA_02721	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02722	COG1279	arginine transmembrane transporter activity
AFMDGAFA_02726	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AFMDGAFA_02727	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AFMDGAFA_02728	COG0006	proline dipeptidase activity
AFMDGAFA_02736	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AFMDGAFA_02741	COG3384	dioxygenase
AFMDGAFA_02743	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AFMDGAFA_02744	COG2878	Part of a membrane complex involved in electron transport
AFMDGAFA_02745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AFMDGAFA_02749	COG0768	penicillin binding
AFMDGAFA_02750	COG0742	ribosomal rna small subunit methyltransferase
AFMDGAFA_02753	COG0830	nickel cation binding
AFMDGAFA_02755	COG0804	urea catabolic process
AFMDGAFA_02765	COG1253	flavin adenine dinucleotide binding
AFMDGAFA_02766	COG2851	Citrate transporter
AFMDGAFA_02776	COG1773	rubredoxin
AFMDGAFA_02777	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AFMDGAFA_02779	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02784	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AFMDGAFA_02785	COG4181	ATPase activity
AFMDGAFA_02794	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AFMDGAFA_02798	COG0306	phosphate transporter
AFMDGAFA_02801	COG3958	Transketolase
AFMDGAFA_02802	COG3959	Transketolase, thiamine diphosphate binding domain
AFMDGAFA_02803	COG2271	Major facilitator Superfamily
AFMDGAFA_02804	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_02805	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02809	COG2223	nitrite transmembrane transporter activity
AFMDGAFA_02810	COG2207	Transcriptional regulator
AFMDGAFA_02811	COG2066	Belongs to the glutaminase family
AFMDGAFA_02812	COG0242	peptide deformylase activity
AFMDGAFA_02813	COG0477	Major facilitator Superfamily
AFMDGAFA_02815	COG0028	Belongs to the TPP enzyme family
AFMDGAFA_02818	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_02819	COG2267	carboxylic ester hydrolase activity
AFMDGAFA_02821	COG2271	Major facilitator Superfamily
AFMDGAFA_02822	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFMDGAFA_02824	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_02828	COG1414	Transcriptional regulator
AFMDGAFA_02831	COG1024	Enoyl-CoA hydratase
AFMDGAFA_02833	COG1215	transferase activity, transferring glycosyl groups
AFMDGAFA_02834	COG0726	polysaccharide deacetylase
AFMDGAFA_02834	COG1649	PFAM Uncharacterised BCR, COG1649
AFMDGAFA_02836	COG4681	YaeQ
AFMDGAFA_02838	COG0523	cobalamin synthesis protein
AFMDGAFA_02840	COG1607	acyl-coa hydrolase
AFMDGAFA_02842	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AFMDGAFA_02843	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AFMDGAFA_02844	COG1309	transcriptional regulator
AFMDGAFA_02849	COG2040	homocysteine
AFMDGAFA_02850	COG0531	amino acid
AFMDGAFA_02856	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFMDGAFA_02857	COG0477	Major facilitator Superfamily
AFMDGAFA_02866	COG0405	Gamma-glutamyltransferase
AFMDGAFA_02867	COG2814	Major facilitator Superfamily
AFMDGAFA_02869	COG2050	protein possibly involved in aromatic compounds catabolism
AFMDGAFA_02872	COG1090	epimerase
AFMDGAFA_02876	COG0420	3'-5' exonuclease activity
AFMDGAFA_02881	COG0735	belongs to the Fur family
AFMDGAFA_02882	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AFMDGAFA_02886	COG0121	glutamine amidotransferase
AFMDGAFA_02889	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFMDGAFA_02891	COG0210	DNA helicase
AFMDGAFA_02893	COG2885	chlorophyll binding
AFMDGAFA_02894	COG0204	Acyl-transferase
AFMDGAFA_02897	COG2894	cell division
AFMDGAFA_02900	COG1280	lysine exporter protein (LysE YggA)
AFMDGAFA_02901	COG1674	ftsk spoiiie
AFMDGAFA_02901	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AFMDGAFA_02902	COG0492	ferredoxin-NADP+ reductase activity
AFMDGAFA_02903	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AFMDGAFA_02905	COG0456	acetyltransferase
AFMDGAFA_02914	COG1981	membrane
AFMDGAFA_02917	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AFMDGAFA_02917	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AFMDGAFA_02921	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_02923	COG0657	acetylesterase activity
AFMDGAFA_02925	COG0473	3-isopropylmalate dehydrogenase activity
AFMDGAFA_02926	COG0583	DNA-binding transcription factor activity
AFMDGAFA_02930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AFMDGAFA_02935	COG0564	pseudouridine synthase activity
AFMDGAFA_02937	COG0358	DNA primase activity
AFMDGAFA_02940	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AFMDGAFA_02945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFMDGAFA_02952	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AFMDGAFA_02954	COG0351	phosphomethylpyrimidine kinase
AFMDGAFA_02954	COG0352	thiamine-phosphate diphosphorylase activity
AFMDGAFA_02954	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AFMDGAFA_02955	COG1652	LysM domain
AFMDGAFA_02960	COG1399	metal-binding, possibly nucleic acid-binding protein
AFMDGAFA_02961	COG3101	peptidyl-lysine hydroxylation
AFMDGAFA_02962	COG0009	L-threonylcarbamoyladenylate synthase
AFMDGAFA_02963	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AFMDGAFA_02964	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AFMDGAFA_02967	COG4106	trans-aconitate 2-methyltransferase activity
AFMDGAFA_02970	COG0596	Alpha beta hydrolase
AFMDGAFA_02970	COG2226	methyltransferase
AFMDGAFA_02970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AFMDGAFA_02971	COG1877	trehalose-phosphatase activity
AFMDGAFA_02972	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AFMDGAFA_02973	COG2223	nitrite transmembrane transporter activity
AFMDGAFA_02977	COG1196	nuclear chromosome segregation
AFMDGAFA_02979	COG0730	response to heat
AFMDGAFA_02982	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFMDGAFA_02984	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFMDGAFA_02994	COG0489	protein tyrosine kinase activity
AFMDGAFA_02996	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFMDGAFA_02996	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFMDGAFA_03002	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AFMDGAFA_03003	COG2081	HI0933 family
AFMDGAFA_03005	COG0668	transmembrane transport
AFMDGAFA_03009	COG0583	DNA-binding transcription factor activity
AFMDGAFA_03014	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AFMDGAFA_03015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AFMDGAFA_03021	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AFMDGAFA_03029	COG0745	RESPONSE REGULATOR receiver
AFMDGAFA_03032	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFMDGAFA_03044	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFMDGAFA_03047	COG0583	DNA-binding transcription factor activity
AFMDGAFA_03053	COG0583	DNA-binding transcription factor activity
AFMDGAFA_03056	COG0583	DNA-binding transcription factor activity
AFMDGAFA_03059	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AFMDGAFA_03060	COG2814	Major facilitator Superfamily
AFMDGAFA_03061	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_03062	COG0583	DNA-binding transcription factor activity
AFMDGAFA_03063	COG1063	alcohol dehydrogenase
AFMDGAFA_03069	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AFMDGAFA_03070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AFMDGAFA_03075	COG2132	Multicopper oxidase
AFMDGAFA_03077	COG0561	phosphatase activity
AFMDGAFA_03078	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AFMDGAFA_03083	COG1214	PFAM Peptidase M22, glycoprotease
AFMDGAFA_03094	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AFMDGAFA_03096	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AFMDGAFA_03097	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AFMDGAFA_03098	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFMDGAFA_03110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AFMDGAFA_03112	COG1846	Transcriptional regulator
AFMDGAFA_03113	COG1764	response to oxidative stress
AFMDGAFA_03121	COG0037	tRNA processing
AFMDGAFA_03123	COG0248	Ppx GppA phosphatase
AFMDGAFA_03128	COG0072	phenylalanine-tRNA ligase activity
AFMDGAFA_03137	COG1238	metal cluster binding
AFMDGAFA_03138	COG0625	glutathione transferase activity
AFMDGAFA_03142	COG3028	Belongs to the UPF0307 family
AFMDGAFA_03143	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AFMDGAFA_03147	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AFMDGAFA_03148	COG0617	tRNA 3'-terminal CCA addition
AFMDGAFA_03149	COG1555	photosystem II stabilization
AFMDGAFA_03150	COG3956	TIGRFAM MazG family protein
AFMDGAFA_03152	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AFMDGAFA_03156	COG0784	Response regulator, receiver
AFMDGAFA_03156	COG2205	protein histidine kinase activity
AFMDGAFA_03156	COG5002	protein histidine kinase activity
AFMDGAFA_03157	COG1024	Enoyl-CoA hydratase
AFMDGAFA_03158	COG2084	Dehydrogenase
AFMDGAFA_03159	COG3622	Belongs to the hyi family
AFMDGAFA_03165	COG0697	spore germination
AFMDGAFA_03167	COG2814	Major facilitator Superfamily
AFMDGAFA_03168	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFMDGAFA_03170	COG0583	DNA-binding transcription factor activity
AFMDGAFA_03171	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AFMDGAFA_03173	COG0084	hydrolase, TatD family'
AFMDGAFA_03176	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AFMDGAFA_03187	COG0440	acetolactate synthase activity
AFMDGAFA_03188	COG0028	Belongs to the TPP enzyme family
AFMDGAFA_03193	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFMDGAFA_03194	COG0577	efflux transmembrane transporter activity
AFMDGAFA_03194	COG1136	(ABC) transporter
AFMDGAFA_03195	COG1538	Outer membrane efflux protein
AFMDGAFA_03198	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AFMDGAFA_03199	COG1162	GTPase activity
AFMDGAFA_03201	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AFMDGAFA_03205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AFMDGAFA_03206	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_03214	COG2986	histidine ammonia-lyase
AFMDGAFA_03216	COG1216	Glycosyl transferase, family 2
AFMDGAFA_03217	COG0318	PFAM AMP-dependent synthetase and ligase
AFMDGAFA_03219	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFMDGAFA_03228	COG1426	Protein conserved in bacteria
AFMDGAFA_03235	COG0793	Belongs to the peptidase S41A family
AFMDGAFA_03238	COG2267	carboxylic ester hydrolase activity
AFMDGAFA_03240	COG1012	belongs to the aldehyde dehydrogenase family
AFMDGAFA_03241	COG3265	gluconokinase activity
AFMDGAFA_03243	COG0800	Aldolase
AFMDGAFA_03245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFMDGAFA_03246	COG0857	belongs to the CobB CobQ family
AFMDGAFA_03246	COG0280	phosphate acetyltransferase
AFMDGAFA_03247	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AFMDGAFA_03247	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AFMDGAFA_03251	COG0740	serine-type endopeptidase activity
AFMDGAFA_03253	COG4774	siderophore transport
AFMDGAFA_03255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AFMDGAFA_03257	COG2813	Specifically methylates the guanine in position
AFMDGAFA_03257	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AFMDGAFA_03277	COG0788	formyltetrahydrofolate deformylase activity
AFMDGAFA_03282	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AFMDGAFA_03282	COG4651	solute:proton antiporter activity
AFMDGAFA_03286	COG0724	RNA recognition motif
AFMDGAFA_03287	COG0210	DNA helicase
AFMDGAFA_03292	COG1733	regulation of RNA biosynthetic process
AFMDGAFA_03294	COG2900	Belongs to the SlyX family
AFMDGAFA_03295	COG0488	(ABC) transporter
AFMDGAFA_03296	COG1280	lysine exporter protein (LysE YggA)
AFMDGAFA_03297	COG1560	Kdo2-lipid A biosynthetic process
AFMDGAFA_03299	COG1301	dicarboxylic acid transport
AFMDGAFA_03310	COG0473	3-isopropylmalate dehydrogenase activity
AFMDGAFA_03321	COG0583	DNA-binding transcription factor activity
AFMDGAFA_03323	COG0625	glutathione transferase activity
AFMDGAFA_03324	COG2378	regulation of single-species biofilm formation
AFMDGAFA_03325	COG0546	phosphoglycolate phosphatase activity
AFMDGAFA_03327	COG1530	ribonuclease E activity
AFMDGAFA_03328	COG0318	PFAM AMP-dependent synthetase and ligase
AFMDGAFA_03331	COG0583	DNA-binding transcription factor activity
AFMDGAFA_03332	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_03333	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AFMDGAFA_03335	COG0534	Mate efflux family protein
AFMDGAFA_03338	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AFMDGAFA_03344	COG0493	'glutamate synthase
AFMDGAFA_03344	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AFMDGAFA_03346	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AFMDGAFA_03347	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFMDGAFA_03350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AFMDGAFA_03352	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AFMDGAFA_03352	COG0644	oxidoreductase
AFMDGAFA_03354	COG0425	Belongs to the sulfur carrier protein TusA family
AFMDGAFA_03355	COG4535	Mg2 and Co2 transporter CorC
AFMDGAFA_03357	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFMDGAFA_03361	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFMDGAFA_03362	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AFMDGAFA_03362	COG0475	glutathione-regulated potassium exporter activity
AFMDGAFA_03365	COG0484	heat shock protein binding
AFMDGAFA_03366	COG0789	Transcriptional regulator
AFMDGAFA_03371	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AFMDGAFA_03372	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AFMDGAFA_03373	COG1074	ATP-dependent DNA helicase activity
AFMDGAFA_03374	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AFMDGAFA_03378	COG2226	methyltransferase
AFMDGAFA_03382	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AFMDGAFA_03385	COG2111	Na H antiporter
AFMDGAFA_03385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AFMDGAFA_03386	COG1006	Multisubunit Na H antiporter MnhC subunit
AFMDGAFA_03387	COG0651	ATP synthesis coupled electron transport
AFMDGAFA_03388	COG1863	multisubunit Na H antiporter MnhE subunit
AFMDGAFA_03389	COG2212	antiporter activity
AFMDGAFA_03390	COG1320	monovalent cation:proton antiporter activity
AFMDGAFA_03393	COG0195	Participates in both transcription termination and antitermination
AFMDGAFA_03400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AFMDGAFA_03403	COG0237	dephospho-CoA kinase activity
AFMDGAFA_03405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFMDGAFA_03408	COG0497	DNA recombination
AFMDGAFA_03410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AFMDGAFA_03416	COG2169	Transcriptional regulator
AFMDGAFA_03416	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AFMDGAFA_03417	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFMDGAFA_03430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AFMDGAFA_03433	COG0326	Molecular chaperone. Has ATPase activity
AFMDGAFA_03436	COG2056	Na+-H+ antiporter family
AFMDGAFA_03437	COG0596	Alpha beta hydrolase
AFMDGAFA_03456	COG0546	phosphoglycolate phosphatase activity
AFMDGAFA_03457	COG1716	ATPase activity
AFMDGAFA_03466	COG0181	hydroxymethylbilane synthase activity
AFMDGAFA_03468	COG3275	phosphorelay sensor kinase activity
AFMDGAFA_03472	COG1538	Outer membrane efflux protein
AFMDGAFA_03473	COG0697	spore germination
AFMDGAFA_03479	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AFMDGAFA_03480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AFMDGAFA_03481	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFMDGAFA_03482	COG0772	Belongs to the SEDS family
AFMDGAFA_03487	COG4974	Belongs to the 'phage' integrase family
AFMDGAFA_03488	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AFMDGAFA_03490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AFMDGAFA_03492	COG2197	response regulator
AFMDGAFA_03495	COG0793	Belongs to the peptidase S41A family
AFMDGAFA_03496	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AFMDGAFA_03497	COG0795	lipopolysaccharide-transporting ATPase activity
AFMDGAFA_03505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AFMDGAFA_03505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AFMDGAFA_03508	COG0347	Belongs to the P(II) protein family
AFMDGAFA_03510	COG0606	chelatase, subunit chli
AFMDGAFA_03512	COG0659	secondary active sulfate transmembrane transporter activity
AFMDGAFA_03513	COG0589	response to stress
AFMDGAFA_03522	COG0606	chelatase, subunit chli
AFMDGAFA_03525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFMDGAFA_03529	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AFMDGAFA_03532	COG0318	PFAM AMP-dependent synthetase and ligase
AFMDGAFA_03534	COG0477	Major facilitator Superfamily
AFMDGAFA_03535	COG2860	membrane
AFMDGAFA_03536	COG3012	SEC-C Motif Domain Protein
AFMDGAFA_03537	COG1253	flavin adenine dinucleotide binding
AFMDGAFA_03539	COG0477	Major facilitator Superfamily
AFMDGAFA_03541	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFMDGAFA_03548	COG0655	NAD(P)H dehydrogenase (quinone) activity
AFMDGAFA_03550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AFMDGAFA_03557	COG1309	transcriptional regulator
AFMDGAFA_03564	COG0758	DNA mediated transformation
AFMDGAFA_03566	COG0697	spore germination
AFMDGAFA_03567	COG1309	transcriptional regulator
AFMDGAFA_03570	COG0386	Belongs to the glutathione peroxidase family
AFMDGAFA_03584	COG1121	(ABC) transporter
AFMDGAFA_03585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AFMDGAFA_03586	COG1280	lysine exporter protein (LysE YggA)
AFMDGAFA_03587	COG2837	iron assimilation
AFMDGAFA_03588	COG0281	malic enzyme
AFMDGAFA_03597	COG0519	Catalyzes the synthesis of GMP from XMP
AFMDGAFA_03597	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AFMDGAFA_03598	COG4399	Belongs to the UPF0754 family
AFMDGAFA_03599	COG2259	Doxx family
AFMDGAFA_03600	COG0586	Pfam SNARE associated Golgi protein
AFMDGAFA_03603	COG1192	Involved in chromosome partitioning
AFMDGAFA_03605	COG0271	Belongs to the BolA IbaG family
AFMDGAFA_03614	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_03615	COG0318	PFAM AMP-dependent synthetase and ligase
AFMDGAFA_03616	COG2197	response regulator
AFMDGAFA_03618	COG3916	Acyl-homoserine-lactone synthase
AFMDGAFA_03619	COG0477	Major facilitator Superfamily
AFMDGAFA_03620	COG1024	Enoyl-CoA hydratase
AFMDGAFA_03621	COG1024	Enoyl-CoA hydratase
AFMDGAFA_03622	COG1960	acyl-CoA dehydrogenase activity
AFMDGAFA_03623	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AFMDGAFA_03627	COG1113	amino acid transport
AFMDGAFA_03628	COG1113	amino acid transport
AFMDGAFA_03629	COG0251	oxidation-reduction process
AFMDGAFA_03637	COG0564	pseudouridine synthase activity
AFMDGAFA_03652	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AFMDGAFA_03655	COG1802	Transcriptional regulator
AFMDGAFA_03656	COG1448	Aminotransferase
AFMDGAFA_03657	COG0277	FAD linked oxidase domain protein
AFMDGAFA_03659	COG2186	Transcriptional regulator
AFMDGAFA_03661	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFMDGAFA_03662	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AFMDGAFA_03665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AFMDGAFA_03666	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AFMDGAFA_03671	COG0438	transferase activity, transferring glycosyl groups
AFMDGAFA_03677	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AFMDGAFA_03683	COG0728	peptidoglycan biosynthetic process
AFMDGAFA_03684	COG3023	N-Acetylmuramoyl-L-alanine amidase
AFMDGAFA_03695	COG0546	phosphoglycolate phosphatase activity
AFMDGAFA_03696	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_03700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AFMDGAFA_03701	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AFMDGAFA_03702	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFMDGAFA_03703	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AFMDGAFA_03704	COG1116	anion transmembrane transporter activity
AFMDGAFA_03705	COG1309	transcriptional regulator
AFMDGAFA_03706	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AFMDGAFA_03708	COG0196	riboflavin kinase activity
AFMDGAFA_03709	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AFMDGAFA_03711	COG1047	Peptidyl-prolyl cis-trans
AFMDGAFA_03718	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AFMDGAFA_03719	COG0657	acetylesterase activity
AFMDGAFA_03723	COG0583	DNA-binding transcription factor activity
AFMDGAFA_03729	COG2951	lytic endotransglycosylase activity
AFMDGAFA_03730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AFMDGAFA_03733	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AFMDGAFA_03735	COG0671	phosphoesterase, PA-phosphatase related
AFMDGAFA_03736	COG0861	Integral membrane protein TerC family
AFMDGAFA_03738	COG0754	glutathionylspermidine amidase activity
AFMDGAFA_03740	COG0402	S-adenosylhomocysteine deaminase activity
AFMDGAFA_03743	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AFMDGAFA_03744	COG1230	cation diffusion facilitator family transporter
AFMDGAFA_03747	COG0706	membrane insertase activity
AFMDGAFA_03754	COG4691	Plasmid stability protein
AFMDGAFA_03762	COG0798	PFAM Bile acid sodium symporter
AFMDGAFA_03768	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFMDGAFA_03778	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AFMDGAFA_03784	COG0659	secondary active sulfate transmembrane transporter activity
AFMDGAFA_03785	COG0589	response to stress
AFMDGAFA_03796	COG0501	Belongs to the peptidase M48B family
AFMDGAFA_03834	COG0739	heme binding
AFMDGAFA_03839	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFMDGAFA_03842	COG1192	Involved in chromosome partitioning
AFMDGAFA_03852	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AFMDGAFA_03872	COG3505	Type IV secretory pathway VirD4
AFMDGAFA_03878	COG1525	nuclease
AFMDGAFA_03894	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFMDGAFA_03900	COG0640	Transcriptional regulator
AFMDGAFA_03915	COG3077	Addiction module antitoxin, RelB DinJ family
AFMDGAFA_03918	COG1028	Short-chain dehydrogenase reductase Sdr
AFMDGAFA_03919	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AFMDGAFA_03929	COG0583	DNA-binding transcription factor activity